Automation and Digitalization in Upstream Process Development at Roche Pharma Cell Culture Research

Sponsored by: Roche CustomBiotech

Focused on:

  • Automation
  • Upstream Process Development

Date: 24 September


Time: 4PM London/11AM New York

96-well plate: a streamlined format for cell culture monitoring with Cedex Bio HT Analyzer

A myriad of factors are decisive in the development of successful cell culture upstream processes. Efficiency in testing and evaluating these parameters is a key consideration for setups and workflows that is often solved through robotics in different fields. The ultimate goal for modern cell culture upstream processes is a fully automated system for the repeated, controlled and preferably hands-off monitoring of multiple concurrent processes, from sample collection through data analysis and resulting feedback loops.

At Roche Pharma Cell Culture Research, highly parallelized bioprocessing using microscale bioreactors (bioreactor farms) enabled such high-throughput efficiency but called for an innovative solution to capture and analyze data from multiple, concurrently running fermenters.

Join this webinar to

  • See the Roche set-up for high throughput sample testing in action

  • Learn about the efficient workflow with a pipetting robot, the recently integrated 96 well plate and smart data processing

Presented by

Dr. Timo Frensing,

Senior Scientist Roche Pharma Research and Early Development

Timo studied biology at the University of Bielefeld (Germany) and holds a Ph.D. in the field of developmental biology (2007). He did a postdoc at the Max Planck Institute for Dynamics of Complex Technical Systems in Magdeburg (Germany) working on cell culture-based influenza vaccine production where he then became a team leader and later assistant professor. Since 2016 Timo has been a lab head at Roche Pharmaceuticals in Penzberg working on early stage upstream process development and driving automation efforts in this field.

Key Learning Objectives

  • Understand the needs and considerations that lead to the current automation of upstream process development at Roche Pharma and benefit from lessons learned.
  • Be among the first to learn about the newly developed 96-well plate for the Cedex Bio HT Analyzer and how it enables the next step towards full automation.
  • See the automation setup in action in a high throughput environment at Roche Pharma - with microscale bioreactors (ambr farm) and Cedex Analyzers.


  • Biomanufacturing Bioprocess Control
  • Bioprocess Analytics
  • Director
  • Manager
  • Technician
  • Scientist
  • Compliance
  • Engineering
  • Quality Assurance
  • Quality Control
  • Regulatory Affairs
  • Research and Development
  • Validation
  • Release Testing
  • Upstream Process Development
  • Upstream Process Manufacturing