Immunotherapy is a powerful tool in the targeted treatment of a wide range of disease pathologies and the number of immunotherapy drugs in the discovery pipeline continues to grow. Approaches can include switching off or restoring balance to aberrant immune responses (such as those in autoimmune disease or allergy) or switching on beneficial immune responses (such as those that can drive in tumour cell clearance in cancer).
Accelerating immunotherapy drug development requires advanced platforms to test the efficacy, and understand their mode of action. In vivo success does not always translate to man and such models are often not compatible with biologics designed for use in humans. As such, sophisticated in vitro models that recapitulate in vivo processes are indispensable.
In this webinar, we discuss the key players targeted in immunotherapy and how these cells and processes can be assessed in vitro. We also provide approaches for selecting the most appropriate assay for your target of interest and requirements.
In addition to showcasing innovative in vitro assays for immunotherapy drug discovery, this webinar will also summarise the current challenges, considerations, and emerging areas within the field. There will also be a live Q&A session where you’ll be able to put your questions to our expert..
Register now to save your seat and following the webinar, you will receive a link to a recording of the presentation.
Rhoanne McPherson is a Principal Scientist at Concept Life Sciences, which is based at Edinburgh’s BioQuarter campus. After obtaining a PhD from the University of Edinburgh in 2012, she spent several years as a post-doctoral scientist focussing on mechanisms of immune pathology and potential therapeutic interventions. Throughout these roles, Rhoanne built expertise the role of checkpoint inhibitors in inducing and maintaining T cell tolerance. In 2017 She moved to Concept Life Sciences (formerly Aquila BioMedical), where her main areas of focus are immuno-oncology and autoimmune inflammation and she is actively involved in further developing Concept’s innovative platform of in vitro and in vivo assays to assist and accelerate immunotherapy drug discovery.
Key Learning Objectives
Understand the key target cells for immunotherapy
Discover how in vitro assays can be used to model in vivo immune responses
Learn how to select the most appropriate assay for your drug target of interest
Challenges and emerging areas in immunotherapy drug discovery