Want to reduce Time to Clinic for your Viral Vector?

Sponsored by: Sartorius Stedim Biotech

Focused on:

  • Viral Vectors
  • Downstream Process Development

Date: 6 December


Time: 3PM London/10AM New York

High-Throughput Solutions for Downstream Process Development

Viral vectors have become one of the most rapidly evolving and promising fields in vaccinology and regenerative medicine. The development of the Downstream Process is challenging because each vector has its own properties. There is not one-fit-all solution. How then should process development scientists approach the development of a viral vector purification process, knowing that each process is unique?

This webinar will give you an overview of the Sartorius approach to accelerate the development of Downstream Processing, combining our well proven technologies – such as membrane chromatography and tangential flow filtration – with state-of-the art automated systems and Design of Experiment Software.

The presentation will include an introduction to the first ambr® system applied to Downstream Processing. ambr® crossflow is a benchtop system optimised for ultrafiltration and diafiltration applications, capable of performing up to 16 trials in parallel.
Please register to reserve your spot for this exciting webinar and we look forward to welcoming you to our presentation.

Presented by

Amélie Boulais,

Vaccine Platform Marketing Manager

Amélie Boulais started her collaboration with Sartorius in 2008 as Application Specialist for the Purification Technologies division, responsible for Southern Europe.

In 2012, she became membrane chromatography and virus clearance project manager, covering Europe. She was focusing on polishing and virus clearance. She became part of the Process Development Consultant team in 2015, supporting and advising actors of the biopharma industry in their development from Upstream to final filling operations.

She joined the Bioprocess Platform team in 2016, taking over the responsibility of vaccine applications. She is analysing the trends of the vaccine industry in order to develop fully scalable platforms with the required associated process development support and related services for vaccine applications. Amélie graduated from ENSTBB (Biotechnology Engineering Institute of Bordeaux, France) and holds a Biotechnology Engineer degree.

Dr Maria Mellado,

Application Specialist, Separation KAM, Sartorius Stedim Biotech

Dr. Maria Mellado earned her M.Sc. degree in Chemical Engineering from the Federal University of Rio de Janeiro with focus on recombinant protein purification with membrane adsorbers. She then earned her Ph.D. in Engineering and Technology Sciences from the New University of Lisbon, Animal Cell Technology Unit at IBET where she studied the assembly of rotavirus-like particles produced in insect cells. Upon completing doctoral studies she worked with biosimilar downstream development at University of Rio de Janeiro as a post-doc scientist. In 2012 she joined Sartorius Stedim Biotech as Application Specialist giving technical support to customers in Separation.

Throughout the years she has gained vast experience in vaccine and viral vector downstream processing using technologies such as crossflow, membrane chromatography and sterilizing grade filtration.

Key Learning Objectives

  • Developing viral vector downstream processes
  • Latest solutions to speed-up process development
  • High Throughput Process Development of ultrafiltration / diafiltration with ambr®
  • Discovering a platform approach for viral vector manufacturing


  • Process Development Scientists
  • Process Development Managers
  • Process Engineers
  • Engineering Directors